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HairAid.com > Database of Drugs for Hair Loss

Hair Loss Drugs: Reductase Inhibitors



Reductase Inhibitors

FCE - dual inhibitors
FCE 28260
FCE 28175
FCE 27837

MK Inhibitors
MK 0434
MK 0963
MK 386

FK Nonsteroidal Inhibitors
FK 143

LY Nonsteroidal Inhibitors
LY 191704

SK&F Inhibitors
SK&F 105657

Dutasteride (Avodart, GI198745)

Finasteride (Propecia, Proscar)

Turosteride

Azelaic acid

Zinc sulphate

CS 891


Turosteride - competitive and specific inhibitor of Type II 5a-reductase.

Competitive and specific inhibitor of Type II 5a-reductase.

Mechanism:
Turosteride blocks the peripheral conversion of testosterone to DHT by type II 5a-reductase in competitive mode, res...click for details

Azelaic acid - 5 alpha-reductase inhibitor.

It was found, that Azelaic acid posses strong 5 alpha-reductase inhibition activity in skin.

Currently mechanism of its reductase inhibition activity is unknown. Its topical action was tested...click for details

Zinc sulphate - 5 alpha-reductase inhibitor.

It was found, that zinc sulphate posses strong 5 alpha-reductase [mainly type 1 isoenzyme] inhibition activity in skin.

Currently mechanism of its reductase inhibition activity is unknown.Inhib...click for details
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